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The impact of the HYPITAT I trial on obstetric management and outcomes for gestational hypertension and preeclampsia

Speaker: Dr. Catherine De Sonnaville
Date recorded: January 2019

Dr. De Sonnaville describes the HYPITAT 1 trial, highlighting the results showing the beneficial effects of induction of labor in pregnancies complicated by hypertensive disorders in term pregnancies. The recommendation of inducing patients with hypertensive disorders of pregnancy at term has been adopted by national guidelines. The study involved adult patients, singleton pregnancies in the cephalic presentation, at 36-41 weeks gestation. They had two cohorts – 1. Pregnancies complicated by hypertensive disorders – gestational hypertension or Preeclampsia and 2. Pregnancies not complicated by hypertensive disorders. The outcomes were onset of labor, maternal complications and neonatal complications. They compared the proportions of the period before the trial (2000-2005) to the period after the trial (2008-2014). They performed a subgroup analysis, compared the HYPITAT recruiting hospitals to the non-recruiting hospitals for the patients with hypertensive disorders.

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The impact of the HYPITAT I trial on obstetric management and outcomes for gestational hypertension and preeclampsia
Select the "View On-Demand Recording" button to begin.
Select the "View On-Demand Recording" button to begin. Learning Objectives: 1. Be able to describe the outcomes of the HYPITAT 1 trial, and the primary aim of the current study. 2. Be able to demonstrate an understanding of the study design, specifically the two patient cohorts and timeframe in which they were compared. 3. Demonstrate an understanding of the population health impact of the HYPITAT 1 trial, as revealed in the Netherlands, specifically on induction of labor, mode of delivery, and occurrence of maternal and neonatal outcomes. 4. Identify the impact of the HYPITAT 1 trial on HYPITAT 1 participating hospitals compared to non-participating hospitals.
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